Supporting Your Immune System Is Simple

As the novel coronavirus spreads around the world, so is a lot of misinformation about how people can protect themselves. Predictably, the pandemic has energized brands and influencers hawking nutritional supplements and other products that they claim can give immune systems a quick and easy “boost” to ward off this coronavirus and the resulting disease, COVID-19.

Such marketing often exasperates immunologists, who stress that it’s not really possible to boost otherwise healthy immune systems, explains Sheena Cruickshank, an immunologist at the UK’s University of Manchester. Nor is that something you’d want, even if it were a possibility: when people develop severe forms of COVID-19, many experts believe it’s because their immune systems are spiraling into overdrive and overwhelming their bodies.

We just need the nuts and bolts of our immune machinery to work normally. People should strive to have a healthy baseline, says Lisa Gralinksi, a virologist who studies coronaviruses at the University of North Carolina at Chapel Hill. “If they do unfortunately get infected, they’ll be in the best possible situation to fight off this infection and stay healthy,” she says. Thankfully, there are some solid, science-backed ways to do that.

Get Moving

The first item on the list won’t surprise you: exercise. Studies overwhelmingly agree that people who exercise regularly are less likely to develop seasonal colds and flus, explains David Nieman, an exercise physiologist at the Human Performance Laboratory at Appalachian State University. For instance, in a 2011 study, Nieman and his colleagues tracked over 1,000 adults through the fall and winter and monitored whether they caught a cold and how many days they were sick. They found that those who were most physically active—doing at least 20 minutes of walking, cycling, or other exercise five or more times a week—reported 43 percent fewer sick days than those with largely sedentary lifestyles.

Muscle contractions increase blood flow and raise body temperature, which are both thought to mobilize immune cells that are usually tucked away in our spleens or lymph tissues. The group of immune cells that surge during and after short bouts of exercise, which include neutrophils and natural-killer cells, serve as our frontline defense against invading viruses.

It’s a transient effect, though, so regular exercise is important. (For people in locked-down parts of the world, there are a lot of options for at-home workouts.) 

However, it’s possible to have too much of a good thing. After an hour or so of high-intensity exercise, the body starts to suffer from stress, which can impair immune function. Elite athletes across many disciplines can be particularly susceptible to falling ill, so don’t push yourself too hard. And obviously, for those who are already sick, that’s the time to rest, not exercise, Nieman adds.

Eat Whole Foods

The second step toward a happy immune system is eating a healthy, balanced diet with plenty of fresh vegetables and fruit. Since your grocery trips may be few and far between, it’s advisable to buy frozen fruits and veggies and more shelf-stable items, like apples, oranges, and sturdy greens, to hold you over until your next outing.

The emphasis here is on balanced, Cruickshank explains. Immunologists don’t know of any one food that does the trick. Not only does a diverse diet provide the vitamins and minerals that immune cells need to function normally, but it’s also good for the bacteria that live in the gut, which play an important role in keeping your immune system working properly, she adds. Do your best not to drink too much, either—alcohol is linked to poor immune function.

There’s little conclusive evidence that nutritional supplements like vitamins, iron, or zinc substantially improve immune function. A recent analysis of 25 clinical studies on vitamin D,​​​​ which included over 10,000 patients, did show that the vitamin has a modest effect in protecting against colds. But there was a lot of variation across studies: some showed no effect whatsoever, explains Adrian Martineau, an immunologist at Queen Mary University of London. It may only be useful to supplement if you are deficient in the vitamin

Generally speaking, if you’re getting enough vitamins from your diet, supplements are unlikely to help much, Nieman says. In previous research, he and his colleagues tried giving large doses of vitamin C and E supplements to elite athletes. Neither produced much of an improvement in immune function. “The body doesn’t work that way,” he explains. “I’d tell people to be very wary of any pill or capsule that contains something that supposedly will magically boost the immune system to do its job better.”

Give Your Brain a Break

Getting enough sleep could help, too. In research by Carnegie Mellon University professor Sheldon Cohen and others, people who got less than seven hours of sleep a night were more likely to develop a cold when the researchers exposed them to a cold-causing virus—a finding echoed by some other studies.

Managing stress may also be important. Another study of Cohen’s showed that those who reported more stress in their lives were more likely to develop cold symptoms. One reason for this effect is that the stress hormone cortisol can suppress certain parts of the immune system, Cruickshank says. She recommends simple practices like spending time in nature (if possible) and appreciating small things.

A lot of these habits are understandably difficult to maintain in the midst of a pandemic. There’s still a lot we don’t know about this virus, and the studies noted in this article have largely focused on less harmful pathogens, but these are the best practices to support healthy immune function. However, many health professionals agree that following sane advice to keep our immune systems healthy—engaging in moderate exercise, eating a balanced diet, and avoiding stressing out—is probably our best bet. And that’s not a replacement for the stuff that can help stop COVID-19 from spreading: washing your hands, staying at home, and keeping up with the latest official advice.

Outside Magazine: Health

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